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Health News Results - 119

Rheumatoid arthritis drugs may save lives of patients hospitalized with severe cases of COVID-19, according to a groundbreaking clinical trial.

The findings, first announced in January, have now been peer-reviewed and published in a major medical journal.

"We are delighted that our full results are now published after peer review. This confirms the robustness of our findings, that ...

A number of new treatments for age-related macular degeneration (AMD), a progressive eye disease, are under development. AMD is a leading cause of vision loss in older people.

About 11 million Americans have AMD, which affects part of the eye that allows you to see fine detail. There are two types: wet and dry. Wet AMD is treated with eye injections every month or two, and dry AMD with an...

Getting bitten by a dog or wild animal is frightening, especially for kids, but a new study may help relieve some of the worry about catching rabies.

The rabies prevention treatment KEDRAB is safe and effective for patients 17 and younger, a groundbreaking pediatric clinical trial has shown.

The trial included 30 kids with suspected or confirmed rabies exposure who were treated with...

A new weight-loss drug is almost twice as effective as current medications, clinical trial results show, and experts say it could revolutionize the treatment of obesity.

Overweight and obese people lost an average 15% of their body weight using a weekly injectable 2.4 milligram dose of semaglutide (Ozempic), a new report reveals.

What's more, one-third of all participants lost 20% ...

An experimental antiviral drug known as peginterferon lambda can speed up COVID-19 patients' ability to shed the virus and recover, scientists report.

"One of the important things about this treatment that's different from the other things that have been studied for COVID-19 is that this is working on the person, not on the virus. So it doesn't depend at all on the strain or the sequence ...

Cannabidiol (CBD) products are seemingly everywhere these days, but they won't help cure a cocaine addiction, a Canadian study finds.

CBD, a chemical in the cannabis plant, has long been touted as a treatment for cocaine addiction. But researchers at the University of Montreal Hospital Research Center found that it doesn't lessen addicts' craving for cocaine or reduce their risk of relaps...

Tough limits on carbohydrates in your meals can help get type 2 diabetes under control -- but the benefits typically wane over time, a new research review shows.

The analysis of 23 small trials found that low-carb diets worked better than other eating plans in helping people lose weight and send their type 2 diabetes into remission. That was true, at least, in the first six months.

...

An inhaled medication might make every day physical activity a bit easier for patients with serious scarring of the lungs, a new clinical trial finds.

The study, published online Jan. 13 in the New England Journal of Medicine, involved patients with high blood pressure in the lungs caused by interstitial lung disease (ILD).

ILD is a broad term for progressive scarring of th...

WEDNESDAY, Jan. 13, 2021 -- A single-shot COVID-19 vaccine from Johnson & Johnson has shown very strong results in early clinical trials, potentially providing a significant boost to U.S. vaccination efforts.

The vaccine produced an immune response of all 805 clinical trial participants within two months of inoculation, according to results published Jan. 13 in the New England Journal...

A return to normal life in America might happen sooner than many expect, one of the nation's leading vaccine experts told HD Live! this week.

As the new coronavirus rages across the country, President-elect Joe Biden has set a goal of one million doses of vaccine delivered every day once he takes office. If that ambitious target is realized, everyday conditions in the United States might ...

Stem cells derived from a baby's umbilical cord can help save the lives of the sickest COVID-19 patients, results from a small new clinical trial suggest.

Severely ill COVID patients who received two intravenous doses of stem cells three days apart were much more likely to survive and recover quickly, researchers found.

"The results are quite spectacular," said senior researcher Dr....

For decades, women have commonly been given oxygen during childbirth, but a new research review finds little evidence it benefits newborns.

The American College of Obstetricians and Gynecologists recommends that women be given supplemental oxygen when fetal heart monitoring shows an abnormal heart rate. That's based on the possibility that oxygen deprivation is causing the problem.

...

Because COVID-19 is known to raise the odds for dangerous blood clots, blood thinners have quickly become part of routine care for many hospitalized patients.

But three clinical trials testing full doses of these drugs in COVID-19 patients have now paused recruitment of critically ill patients because the medications could end up doing more harm than good.

According to experts at t...

A mind-body practice that combines meditation and yoga might help people better manage migraine pain, a new clinical trial finds.

The trial, which tested the effects of mindfulness-based stress reduction (MBSR), found that the approach helped relieve migraine sufferers' depression and disability. It also boosted how they rated their quality of life.

MBSR is a standardized, eight-wee...

More women with early-stage breast cancer may be able to safely skip chemotherapy after having surgery, according to initial results from a major clinical trial.

The trial, conducted in nine countries, found that adding chemotherapy to hormone-blocking drugs brought no added benefit to a particular group of patients. Those were postmenopausal women with hormone-sensitive breast cancer tha...

AstraZeneca's COVID-19 vaccine is safe and effective, new data from late-stage trials shows.

Overall, the vaccine protected against symptomatic disease in 70% of cases, according to a team led by researchers from Oxford University in England. Among study volunteers who got a half dose and then a full dose, the rate was 90%, while the rate was 62% in those given two full doses.

Scientists say they may be getting closer to creating a universal flu vaccine.

In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immune responses to a wide range of flu virus strains and subtypes. The immune responses lasted at least 18 months, according to the researchers at Mount Sinai Health System, in New York City.

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The diversity, and therefore the health, of the microbes in your gut is linked to your levels of vitamin D, a new study suggests.

The gut microbiome is composed of bacteria, viruses and other microbes that live in our digestive tracts and are important factors in our health and risk for disease.

In this study, researchers analyzed stool and blood samples from 567 men in six U.S. cit...

Two COVID-19 vaccines are on the verge of approval in the United States, with pharmaceutical companies promising that millions of doses will be available to the first wave of recipients within a matter of weeks.

Creating two vaccines in less than a year is an astonishing achievement, experts say, but the next task could prove even more difficult — convincing Americans that it's safe to ...

A widely used tuberculosis vaccine may help protect people against the new coronavirus or reduce the severity of COVID-19, a new study suggests.

The Bacillus Calmette-Guérin (BCG) was developed in the early 1900s and is given to more than 100 million children worldwide every year.

In the United States, BCG is approved as a vaccine for people at high risk of contracting tuberculosis...

Children should be included in COVID-19 vaccine trials at the earliest possible stage, a leading group of U.S. pediatricians says.

If that's not done, youngsters' lives could be at risk, according to the 67,000-member American Academy of Pediatrics (AAP).

"If we do not add children to these research trials very soon, there will be a significant delay in when children are able to ac...

A procedure that "stuns" pain-sensing nerves might offer relief to people with severe arthritis of the hip or shoulder, a small, preliminary study suggests.

The procedure is a form of radiofrequency ablation, where doctors use needles to send a low-grade electrical current to nerves that are transmitting pain signals from the arthritic joint to the brain. The current heats and damages the...

A Chinese COVID-19 vaccine seems to be safe and effective, early trial results suggest, but one expert says the findings should be regarded with caution.

The CoronaVac vaccine is based on inactivated SARS-CoV-2 virus. It was tested in a phase 1/2 clinical trial that included more than 700 healthy volunteers, ages 18-59, who were recruited in China between April 16 and May 5.

The vac...

A combination of two "targeted" therapies can beat back a rare form of blood cancer -- without the toxic effects of chemotherapy, a new study has found.

In a trial of 63 patients, researchers found that the drug regimen frequently wiped out all signs of the cancer -- a subtype of the blood cancer acute lymphoblastic leukemia (ALL). And at 18 months, 95% of patients were still aliv...

A recently approved rheumatoid arthritis medication appears to be an effective second-line therapy when biologic treatments start to fail, a new clinical trial reports.

Arthritis sufferers treated with upadacitinib had a significantly greater reduction in their symptoms and disease activity than people treated with a standard disease-modifying antirheumatic drug (DMARD), said co-resea...

An experimental drug combination lengthens survival for patients with amyotrophic lateral sclerosis (ALS), new research shows.

A previous clinical trial found that the two-drug combo -- called AMX0035 -- slowed progression of the neurodegenerative disease over six months.

The new clinical trial of 137 patients with the disease, also known as Lou Gehrig's disease, found that ...

A small study suggests that a new procedure that treats part of the intestine just beyond the stomach may allow people with type 2 diabetes to safely stop taking insulin.

The procedure -- which resurfaces the duodenum -- was combined with a popular kind of diabetes medication called GLP-1 receptor agonists (such as Victoza, Trulicity, Ozempic) and counseling on lifestyle factors, such a...

Type 2 diabetes can be tough to control without medication. But for some people, the thought of daily shots makes them delay or avoid starting insulin therapy.

Now, new research offers some hope for those insulin avoiders -- a once-a-week insulin injection may someday replace daily shots.

A phase 2 trial compared the new weekly insulin, called icodec, to the commonly used i...

An immunotherapy drug significantly improved survival in patients with the most common type of bladder cancer, according to a new study.

About 550,000 new cases of bladder cancer are diagnosed worldwide each year, making it the 10th most common type of cancer, the study authors noted.

Chemotherapy is the initial standard of care for advanced bladder cancer. After chemotherap...

A new clinical trial will try to determine whether the measles, mumps and rubella (MMR) vaccine can protect health care workers from being infected with COVID-19.

Hundreds of millions of people have received the MMR vaccine since it was developed nearly 50 years ago. It's usually given to children before age 6. Growing evidence suggests that the vaccine may also prevent COVID-19.

...

An experimental treatment may help slow the progression of the deadly brain disease amyotrophic lateral sclerosis (ALS), a new study finds.

Researchers called the results a promising step in the fight against a devastating and invariably fatal disease. And two advocacy groups are calling for swift action to make the drug available to patients.

ALS is also known as Lou Gehrig...

A slew of "gold standard" clinical trials offer new hope for patients battling severe COVID-19: cheap, common drugs known as corticosteroids appear to cut the death rate by a third.

Publication of new data on treatment with corticosteroids such as hydrocortisone or dexamethasone "represents an important step forward in the treatment of patients with COVID-19," said Dr. Hallie Prescott...

An artificial pancreas system is safe and effective at managing blood sugar levels in kids as young as age 6 with type 1 diabetes, according to a new study.

The system uses a continuous glucose monitor (CGM) to track blood sugar levels and automatically delivers insulin when needed using an insulin pump. It replaces reliance on fingerstick or CGM with delivery of insulin by injection ...

There may be no cure for the common cold, but a spoonful of honey might make it less miserable, a new research review concludes.

Parents have long used honey to soothe kids' sore throats and cough -- probably because their parents did. But the review of 14 clinical trials finds some science to back it up.

Overall, adults and kids given honey had less-severe, less-frequent co...

While there are treatments to alleviate symptoms of Parkinson's disease, there is no known cure or preventive drug. But a recent review offers some encouraging findings.

The review found more than 100 clinical trials are underway around the world that are testing various preventive therapies and treatments for the neurodegenerative disorder.

The large number of trials, and ...

Although minorities are paying a disproportionate price in the rate of COVID-19 illnesses and deaths, they are underrepresented in clinical trials, a new study finds.

The researchers call upon the government, medical journals and funders of research to make sure trials include minorities so that the results can be extrapolated to the U.S. population.

In the Adaptive COVID-...

There is a longstanding fear in the scientific community that pharmaceutical companies could sway the research published in medical journals by paying them for advertising, but a new study reveals that advertising might not be the problem.

"All the available literature suggests that ad revenue should be the real concern, but that's not what we found," said study author S. Scott Graham...

A new injection drug can prevent multiple sclerosis flare-ups better than an existing medication, a clinical trial has found.

The drug, called ofatumumab, beat a standard MS medication in reducing patients' symptom relapses. It also slowed down the progression of their disability over six months.

The researchers said the findings, published Aug. 6 in the New England Journ...

The COVID-19 pandemic has prompted a massive scientific response to the crisis, with more than 1,500 coronavirus studies kicking off between March and mid-May of this year, a new study reports.

Unfortunately, much of this research has sown only confusion, producing precious little scientific evidence of sufficient quality to dramatically improve any understanding of COVID-19, research...

A cream medication that eases skin inflammation might offer a safer treatment option for people with psoriasis, a new clinical trial suggests.

Psoriasis is a chronic skin condition that affects more than 8 million Americans, according to the National Psoriasis Foundation. The disease arises from an abnormal immune response that triggers rapid turnover of skin cells, causing them to pi...

With several potential COVID-19 vaccines now in clinical trials, U.S. policymakers need to plan for the next hurdle: Ensuring Americans actually get vaccinated.

That's according to a new report from the Johns Hopkins Center for Health Security. It lays out recommendations for winning the public's trust of any future vaccine, and helping them access it as easily as possible.

...

A tuberculosis vaccine may help reduce the risk of death from COVID-19, researchers suggest.

Developing countries have lower-than-expected COVID-19 death rates, and a TB vaccine given in countries with high rates of tuberculosis might play a significant role in reducing COVID-19 death rates, according to authors of a new study.

The vaccine, which is routinely given to childr...

U.S. government-funded clinical trials for new cancer treatments have more Black participants than those run by drug companies, but Blacks are still underrepresented in cancer studies, researchers say.

The SWOG Cancer Research Network team analyzed data from 358 clinical trials -- 85 drug industry trials and 273 SWOG trials. They included nearly 94,000 patients who were being treated ...

There's more good news on the effectiveness of the antiviral drug remdesivir against COVID-19, according to new clinical trial results from the drug's maker.

Gilead Sciences said Friday that in a trial involving more than 1,100 patients, remdesivir was associated with improved recovery and a 62% reduced risk of death compared with standard care.

The study also showed tha...

Older, critically ill COVID-19 patients who are given a combination of two common antiretroviral drugs can experience a drastic slowing of their heart rate, French researchers report.

In their study of 41 patients treated with lopinavir and ritonavir twice daily for 10 days, 22% developed a slow heart rate condition called bradycardia. When the drugs were stopped or doses lowered,...

Older adults with healthy hearts probably would benefit from taking a cholesterol-lowering statin, a new study contends.

People 75 and older who were free of heart disease and prescribed a statin wound up with a 25% lower risk of death from any cause and a 20% lower risk of heart-related death, researchers reported July 7 in the Journal of the American Medical Association...

CT scans have been proven to help spot lung cancer early and save lives. Now, updated expert recommendations could double the number of Americans who are eligible for the yearly screening.

The recommendations -- from the U.S. Preventive Services Task Force (USPSTF) -- would expand the definition of "high risk" for lung cancer. That's expected to not only increase the number of people ...

An experimental ultrafast-acting insulin could work four times quicker than current fast-acting formulas, researchers say.

For the study, the researchers focused on a form of insulin called monomeric insulin. Though its structure should, in theory, allow it to act faster, monomeric insulin is too unstable for practical use, so the Stanford University team had to find a way around that...

Data from a five-year clinical trial is adding to growing evidence that deep brain stimulation (DBS) can slow the ravages of Parkinson's disease.

Researchers at Vanderbilt University Medical Center in Nashville, Tenn., said that the therapy appears to curb any worsening of tremor and other symptoms, as well as lessening a patient's need for medications.

"Parkinson's is relen...

There's new evidence that a 2,000-year-old medicine might offer hope against a modern scourge: COVID-19.

The medication, called colchicine, is an anti-inflammatory taken as a pill. It's long been prescribed for gout, a form of arthritis, and its history goes back centuries. The drug was first sourced from the autumn crocus flower.

Doctors also sometimes use colchicine to tre...