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Head-to-Head Study Finds Which Diabetes Meds Are Best for the Heart

There are many medications for type 2 diabetes, but one class may stand out for protecting the heart, a new study suggests.

The study, of thousands of U.S. veterans with diabetes, found that those who added drugs called GLP-1 receptor agonists to their usual regimen were somewhat less likely to suffer a first-time heart attack or stroke in coming years.

That was in comparison to vet...

Eli Lilly to Slash Insulin Prices, Cap Monthly Out-of-Pocket Costs at $35

More Americans will soon be paying less for their insulin.

Eli Lilly, one of the three insulin manufacturers, plans to cut its list prices of the drug by 70% and cap out-of-pocket costs at $35 a month.

"While the current health care system provides access to insulin for most people with diabetes, it still does not provide affordable insulin for everyone, and that needs to change," E...

Too Few Americans With Diabetes Are Getting Recommended Meds

Most Americans with type 2 diabetes are candidates for newer, pricey medications, but few are getting them, a new government study shows.

Researchers found that of U.S. adults with the blood sugar disease, over 80% could stand to benefit from the medications, based on recommendations from the American Diabetes Association (ADA). But only 10% of those people were actually taking the drugs ...

Type 1 Diabetes and Use of 'Off-Label' Drugs: Benefits, but Concerns, Too

While people with type 1 diabetes can see some benefit from newer medications prescribed off-label, there is also risk, and these patients should be monitored closely, according to a new study.

Type 1 diabetes is universally treated with insulin injections, but only about one-fifth of patients achieve blood sugar control with it,

  • Cara Murez HealthDay Reporter
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  • February 20, 2023
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  • Diabetes Med Ozempic in Short Supply as Americans Use It for Weight Loss

    Elon Musk swears by the weight-loss drug Wegovy, and Kim Kardashian is rumored to have used it to shed 16 pounds in three weeks to squeeze into a vintage gown once worn by Marylin Monroe.

    But the intense public demand for Wegovy has triggered a shortage of the diabetes version of the injectable medication, known as Ozempic. That's leaving patients with the blood sugar disease in a real bi...

    Insulin Pumps Ease Diabetes Care. So Why Are Black Patients Less Likely to Get One?

    Insulin pumps can help folks with type 1 diabetes get better control of their disease and minimize how often they inject insulin, and use of the devices has taken off in the past 20 years.

    That's the good news from a new study.

    The not-so-great news is that a large gap in wh...

    Cats Now Have an FDA-Approved Pill to Treat Their Diabetes

    Owners whose cats have diabetes now have a new option to care for the condition in their otherwise healthy pets.

    The U.S. Food and Drug Administration on Thursday approved the first pill to improve control of diabetes in some cats.

    The drug, call...

    Diabetes Drug Metformin Might Keep Severe COVID Away

    A century-old diabetes drug seems to help keep high-risk COVID-19 patients from falling deathly ill, a new study reports.

    Metformin reduced the risk of death from COVID-19 by 44% in a group of diabetics who were taking the drug when they became infected with the coronavirus, according t...

    California's Plan to Make Low-Priced Insulin Could Be Example for Nation

    California's plan to manufacture its own insulin could be a huge money-saver for state residents with diabetes -- and possibly be a model for other states, according to experts.

    Earlier this year, California announced an initiative to bring its own insulin products to market, in response to the steep costs of the lifesaving drug in the United States.

    And if it's successful, it will ...

    Certain Class of Diabetes Meds Could Cut Dementia Risk

    An older class of type 2 diabetes drugs known as thiazolidinediones, or TZDs, may protect you from dementia down the road, according to new research.

    Thiazolidinediones, also known as glitazones, cut dementia risk by 22% among folks at high risk who also had mild or moderate type 2 diabetes when they took these me...

    Over a Million Americans Are Rationing Insulin Due to High Cost

    More than 1 million Americans with diabetes have to ration lifesaving insulin because they can't afford it, a new study shows.

    Many people delayed picking up their insulin prescription, while others took lower doses than they needed, researchers found.

    Exp...

    Big Studies Test Effectiveness of Common Diabetes Meds

    Two common diabetes medications seem to outperform two others when it comes to controlling blood sugar levels, a large U.S. trial has found.

    The trial of more than 5,000 people with type 2 diabetes found that two injection medications -- a long-acting insulin and

  • Amy Norton HealthDay Reporter
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  • September 22, 2022
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  • Experimental Insulin-in-a-Pill Shows Promise in Rat Study

    People with type 1 diabetes who need to inject insulin a few times a day could eventually be switching to an easier-to-take tablet that dissolves inside the cheek.

    Canadian researchers working with rodents report they have created an insulin that could be taken in pill form without most of bein...

    Common Diabetes Drug Januvia May Contain Traces of Carcinogen, FDA Says

    The popular diabetes drug Januvia may contain traces of a probable carcinogen, but patients should keep using the medication because it could be dangerous to stop taking it, the U.S. Food and Drug Administration announced this week.

    Despite the discovery that Nitroso-STG-19 (NTTP) had been found in some samples of the drug, known generically as

  • By Cara Murez HealthDay Reporter
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  • August 12, 2022
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  • Rise in Birth Defects for Babies Whose Fathers Took Common Diabetes Drug

    Babies born to fathers who were taking the common diabetes drug metformin may have a slightly increased risk of certain birth defects, a large new study suggests.

    Among over 1 million babies born in Denmark, just over 3% had a birth defect of some kind. But that rate was roughly 5% among babies whose fathers ...

    When Will Americans With Diabetes Get Relief From High Insulin Prices?

    Katherine Stewart, 16, must take six to 10 insulin shots a day to properly manage her type 1 diabetes.

    Her Highland, Utah, family pays $500 a month out of pocket for her insulin. Before they meet their insurance's deductible, they shell out the cash price of nearly $2,000 a month.

    Now Stewart is preparing to leave the nest, and she doesn't know how she'll be able to afford it.

    Osteoporosis Drug May Keep Type 2 Diabetes at Bay

    A drug widely used to treat osteoporosis might reduce the risk of type 2 diabetes, a new study suggests.

    Taking the drug alendronate (Fosamax) for at least eight years could potentially reduce a person's risk of type 2 diabetes by more than half, compared to people never prescribed the drug, according to findings presented Sunday at the annual meeting of the European Association for the S...

    Diabetes Drug Might Help Women With Preeclampsia Prolong Their Pregnancy

    Metformin, a commonly prescribed diabetes drug, may help stave off preterm birth among women who develop pregnancy-related high blood pressure.

    Preeclampsia is marked by a sudden spike in blood pressure, protein in urine, or other problems during pregnancy. Preterm preeclampsia occurs between 26 and 32 weeks of pregnancy and often leads to early delivery, putting babies at risk. Preemies ...

    Some Diabetes Meds Might Also Lower Alzheimer's Risk

    Older adults who take certain diabetes drugs may see a slower decline in their memory and thinking skills, a new study suggests.

    Researchers in South Korea found that among older people who'd been having memory issues, those using diabetes drugs called DDP-4 inhibitors typically showed a slower progression in those symptoms over the next few years. That was compared with both diabetes-fre...

    When Deductibles Rise, More Diabetes Patients Skip Their Meds

    As many Americans know, today's health insurance plans often come with high deductibles. Those out-of-pocket costs could cause harm: New research shows that 20% of people who have diabetes and high-deductible health plans regularly skip their medications.

    Not keeping up with your diabetes medications comes with the potential risk of an emergency room visit or a hospitalization.

    FDA OKs Automatic Use of a Cheaper Generic  Insulin

    U.S. pharmacists will now be able to automatically substitute a cheaper biosimilar for a more expensive brand-name insulin, the U.S Food and Drug Administration announced Wednesday.

    The agency's approval of an "interchangeable" biosimilar could save diabetics and health plans millions each year, the Associated Press reported. Until now, doctors have had to specifically prescribe ...

    Walmart to Offer Low-Priced Insulin

    TUESDAY, June 29, 2021 (HealthDay News) --Walmart said Tuesday that it will start selling its own private brand of insulin at much lower prices than competing products.

    Insulin prices have skyrocketed in recent years, making it unaffordable for some Americans with diabetes, according to CBS News.

    "We know many people with diabetes struggle to manage the financial burden of ...

    Which Blood Sugar Meds Work Best Against Type 2 Diabetes?

    You have type 2 diabetes, and you are already taking an old standby drug, metformin. But you still need help controlling your blood sugar levels. Which medication would be the best?

    New research pitted several diabetes drugs against each other and came up with an answer: The diabetes drugs Lantus and Victoza were better at controlling blood sugar over time than Amaryl or Januvia.

    "W...

    Weekly Injected Drug Could Boost Outcomes for Patients With Type 2 Diabetes

    People with type 2 diabetes face heightened risks for heart attack and stroke, as well as progressive kidney disease. But a new once-a-week injected drug called efpeglenatide could greatly reduce their odds for those outcomes, new research shows.

    The clinical trial was conducted in over 28 nations and involved more than 4,000 patients with type 2 diabetes.

    Over two years, patients ...

    Poorly Managed Diabetes Raises Odds for More Severe COVID

    Hospitalized patients with diabetes who hadn't been taking their medication had more severe cases of COVID-19, a new study shows.

    "Our results highlight the importance of assessing, monitoring and controlling blood glucose [sugar] in hospitalized COVID-19 patients from the start," said study author Sudip Bajpeyi, associate professor of kinesiology at the University of Texas at El Paso. H...

    America Is Losing the War Against Diabetes

    After years of improvement, Americans with diabetes may be losing some ground in controlling the condition, a new government-funded study shows.

    Researchers found that between 1999 and the early 2010s, U.S. adults with diabetes made substantial gains: A growing percentage had their blood sugar, blood pressure and cholesterol down to recommended levels.

    Since then, the picture has ch...

    Could Certain Diabetes Drugs Fight Asthma, Too?

    Researchers have discovered that when patients who have type 2 diabetes and asthma take a certain class of medication to control their blood sugar, their asthma symptoms also improved.

    Not only could this help diabetes patients who may have less asthma control on asthma medicines, but it could potentially open up new treatment options for those who don't have diabetes.

    The study sho...

    Common Type 2 Diabetes Meds Won't Raise Breast Cancer Risk: Study

    Widely used diabetes and obesity drugs don't increase the risk of breast cancer, a new study indicates.

    The drugs -- called glucagon like peptide-1 receptor agonists or GLP-1 RAs for short -- are effective in treating type 2 diabetes and obesity and in reducing heart disease. But some previous studies have suggested a possible link between them and breast cancer.

    GLP-1RAs include al...

    Could a Drug Prevent Type 1 Diabetes in Those at Risk?

    Just two weeks of treatment with an experimental drug can delay the onset of type 1 diabetes by several years, researchers report.

    The drug, called teplizumab, is already under review by the U.S. Food and Drug Administration based on earlier evidence of its effectiveness.

    If it gets the green light, it would become the first drug approved for delaying type 1 diabetes in high-risk pe...

    Patients With Diabetes Need More Counseling on Low Blood Sugar

    Doctors need to do a better job of discussing low blood sugar with patients who take high-risk diabetes medications such as insulin, researchers say.

    Low blood sugar (hypoglycemia) is the most common serious side effect of diabetes treatment. Severe cases can lead to falls, emergency department visits, and may increase the risk of stroke and death.

    "For patients to have safe diabete...

    Insulin May Not Need Refrigeration, Freeing Up Its Use in Poorer Nations

    Researchers report that insulin can be stored at less-cold temperatures than previously known, potentially simplifying diabetes care for people in warmer regions that have fewer resources.

    Researchers from Doctors Without Borders and the University of Geneva tested insulin storage in real conditions ranging from 77 to 98.6 degrees Fahrenheit for four weeks -- the time it typically takes t...

    Type 2 Diabetes Drug Metformin Could Help Prevent Some Breast Cancers

    Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds.

    Compared to women without diabetes, risk for estrogen-positive breast cancer was 38% lower among women with type 2 diabetes who had used metformin for 10 years or more.

    Metformin did not protect agai...

    Common Diabetes Meds Tied to Serious COVID-19 Complication

    Diabetics who've contracted COVID-19 should suspend their use of a class of common diabetes drugs known as sodium-glucose co-transporter 2 inhibitors (SGLT2i), new research warns.

    People using these medications for diabetes are at risk of a potentially fatal complication called diabetic ketoacidosis (DKA), and it now appears that risk increases even more if they become sick with COVID-19,...

    Diabetes Drug Metformin May Protect the Aging Brain

    A common type 2 diabetes drug called metformin may have an unexpected, but positive, side effect: New research suggests that people taking the drug appear to have significantly slower declines in thinking and memory as they age.

    "Our six-year study of older Australians with type 2 diabetes has uncovered a link between metformin use and slower cognitive [mental] decline and lower deme...

    Once-a-Week Insulin for Type 2 Diabetes Shows Promise in Early Trial

    Type 2 diabetes can be tough to control without medication. But for some people, the thought of daily shots makes them delay or avoid starting insulin therapy.

    Now, new research offers some hope for those insulin avoiders -- a once-a-week insulin injection may someday replace daily shots.

    A phase 2 trial compared the new weekly insulin, called icodec, to the commonly used i...

    Pandemic Means Financial Hardship for Many With Diabetes

    People with diabetes face a higher risk of developing complications from COVID-19, but a new survey reports they have also suffered more economic fallout from the pandemic.

    In June, 18% of people with diabetes were out of work compared to 12% of the general population. And one-third of people with diabetes have lost at least some income since the pandemic began versus about 2...

    In Rare Cases, Diabetes & Cholesterol Drug Combo Could Be Toxic

    Taking the statin Crestor in combination with the diabetes drug canagliflozin (Invokana) may have the potential to trigger statin toxicity, a new case report suggests.

    Although this report details the problem in just one woman, the researchers noted concern because these drugs are taken by millions of people worldwide. These drugs are also increasingly prescribed together.

    Common Diabetes Meds Linked to Higher Odds for a Serious Complication

    People taking a class of diabetes medications called SGLT2s have up to three times the risk for a serious complication called diabetic ketoacidosis (DKA) compared to people taking another drug, new research reveals.

    SGLT2 (sodium-glucose cotransporter-2) inhibitors -- such as Farxiga, Jardiance and Invokana -- are a newer type of oral diabetes medicine. This class of medications is k...

    Animal Tests Point to Possible Path to Ultrafast Insulin

    An experimental ultrafast-acting insulin could work four times quicker than current fast-acting formulas, researchers say.

    For the study, the researchers focused on a form of insulin called monomeric insulin. Though its structure should, in theory, allow it to act faster, monomeric insulin is too unstable for practical use, so the Stanford University team had to find a way around that...

    Patch Pump Device Could Offer Cheaper Insulin Delivery

    Rising prices have grabbed headlines as people struggle to afford their lifesaving insulin, but new research may have found an alternative for people with type 2 diabetes.

    The study found that combining a wearable, patch-like insulin delivery device (called the V-Go) and an older, cheaper insulin could safely help people with type 2 diabetes achieve good blood sugar control.

    ...

    Doctors Describe First Drone Delivery of Diabetes Meds to Patient

    Imagine needing insulin to live but a natural disaster suddenly cuts off access to your medication. New drone technology may one day come to the rescue by making urgent deliveries to remote locations, researchers say.

    The world's first documented drone delivery of medications to a diabetes patient in a difficult-to-reach community is described in a new paper.

    The 16-minute...

    Price Hikes Have Patients Turning to Craigslist for Insulin, Asthma Inhalers

    Maybe you've gone to Craigslist to find a used car or a secondhand couch, but imagine having to turn to the internet to pay for lifesaving drugs.

    It's already happening: A new study found that hundreds of ads were placed on Craigslist for insulin and asthma inhalers during a 12-day period in June 2019.

    "This study shines a light on how deeply some patients are struggling to...

    Drug Duo Speeds Regeneration of Key Cells Lost in Diabetes

    A novel combination of two drugs appeared to spur faster regeneration of insulin-producing beta cells in the pancreas, a preliminary study in mice and human tissue found.

    Beta cells are crucial to making insulin, a hormone that's deficient in people with type 1 and type 2 diabetes.

    The new drug combo pairs an already approved class of type 2 diabetes medications called GLP-...

    Medicare Could Save Billions If Allowed to Negotiate Insulin Prices

    If you don't need insulin, you probably haven't paid much attention to its skyrocketing cost, but new research shows that exorbitant drug pricing eventually affects everyone.

    The study found that in 2017, Medicare spent nearly $8 billion on insulin. The researchers said that if Medicare were allowed to negotiate drug prices like the U.S. Department of Veterans Affairs (VA) can, Medic...

    Big Advances Made Against Diabetes in 2019

    A new artificial pancreas system, drugs that help control blood sugar and protect the heart and the kidneys, a new medication that delays type 1 diabetes, and a new way to track blood sugar throughout the day -- 2019 was a pretty big year in diabetes care.

    "This has been a good year for patients who have diabetes. There have been a lot of changes and there are more options. The...

    FDA Testing Levels of Carcinogen in Diabetes Drug Metformin

    Levels of possible cancer-causing chemicals in metformin diabetes medications are under investigation by the U.S. Food and Drug Administration.

    Metformin is a prescription drug used to control high blood sugar in patients with type 2 diabetes.

    Over the past year and a half, several types of drugs -- including angiotensin II receptor blockers (ARBs) used for high blood pressu...

    Could a Pill Replace Insulin Shots?

    Many people with diabetes have to inject themselves with insulin at least once a day, but new animal research suggests a pill may one day do the trick.

    This experimental pill can withstand the trip through the gastrointestinal tract, scientists report. When it gets to the small intestine, it breaks down into dissolving microneedles that attach to the intestinal wall and release the dr...

    Older Diabetics May Be Getting Too Much Insulin

    Are elderly people with diabetes being overtreated?

    A new study suggests that's so: Older, sicker patients tend to be the ones most likely to still be using insulin to manage their blood sugar, despite guidelines that suggest it's often safer to lower diabetes treatment intensity with age.

    The study found that nearly 20% of people with type 2 diabetes older than 75 were...

    FDA OKs New Pill for Type 2 Diabetes

    A new pill to lower blood sugar for people with type 2 diabetes was approved by the U.S. Food and Drug Administration on Friday.

    The drug, Rybelsus (semaglutide) is the first pill in a class of drugs called glucagon-like peptide (GLP-1) approved for use in the United States. Before Rybelsus, the drug had to be injected.

    "Before this approval, patients did not have an oral GL...

    Keeping Blood Sugar Steady Helps You Live Longer With Diabetes

    If you have type 2 diabetes, keeping your blood sugar levels stable over time may be key to living longer.

    New research finds that people who have more swings in their blood sugar levels were more than twice as likely to die early, compared to folks with more stable blood sugar management.

    The study authors used a test called hemoglobin A1C to measure blood sugar. This com...

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