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New Hope for People With Aggressive Form of Lymphoma

An experimental cancer treatment regimen is achieving full remissions in some patients with aggressive B-cell lymphoma, researchers report. 

The five-drug combination does not include chemotherapy. Rather, it simultaneously zeroes in on several molecular pathways that diffuse large B-cell lymphoma (DLBCL) tumors rely on to survive. B-cell lymphoma is a cancer of cells in the body's i...

Could Tattoos Be Linked to Blood Cancer Risk?

Research suggests that tattoo ink spurs inflammatory changes that might contribute to the development of lymphoma.

The findings are early, however, and more study must be done to confirm any links between tattooing and the blood cancer, Swedish researchers stressed.

"People will likely want to continue to express their identity through tattoos, and therefore it is very important tha...

Strategy Could Expand Stem Cell Donor Pool for People Battling Blood Cancers

An older drug used in a new way could open the path for more patients with potentially deadly blood cancers to receive a lifesaving stem cell transplant, a new study finds.

The drug, cyclophosphamide, could help patients receive a stem cell transplant even if the donor isn't a relative and only partially matches their blood type, researchers report.

Blood cancer patients had a high ...

New Drug Could Be Big Advance Against Rare Blood Cancer

Polycythemia vera is a rare form of blood cancer with few good treatment options, but that may soon change based on the results of a new clinical trial.

An injected experimental drug called rusfertide appears effective in reducing the excess production of red blood cells that's a hallmark of the disease.

"Rusfertide appears to represent a significant step forward in treating polycyt...

Major Study Confirms CT Scans' Link to Blood Cancer Risk in Kids

CT scans are significantly linked to an increased risk of blood cancers in young people, a major multinational study has found.

Analysis of data from nearly 1 million people under 22 who underwent at least one CT scan found a strong and clear link between exposure to the scans' radiation and blood cancers, according to findings published Nov. 9 in the journal

  • Dennis Thompson HealthDay Reporter
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  • November 10, 2023
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  • Weight-Loss Surgery Could Lower Odds for Blood Cancers

    Weight-loss surgery can deliver a host of health benefits, but new research reveals an unexpected one: Getting the surgery was associated with a 40% lower risk of blood cancers.

    Being overweight or obese is a risk factor for several types of cancer, and women with obesity have a higher risk of cancer than men do.

    In the study, researchers used data from the Swedish Obese Subjects (...

    Fracking Tied to Lymphomas, Asthma in New Study

    Research into a possible link between childhood health problems and natural gas wells in western Pennsylvania is wrapping up with some answers.

    Children who lived near these wells were more likely to develop rare lymphoma, the research found.

    In addition, residents of all ages near the wells had increased risk of severe asthma reactions, the Associated Press reported.

    Can Some Cancer Patients Safely Skip Radiation Therapy? New Studies Say Yes

    Radiation therapy might not be necessary in treating some forms of rectal cancer and lymphoma, sparing patients from the toxic treatment, a pair of new clinical trials shows.

    One trial found that rectal cancer patients whose tumors shrink in response to chemotherapy can safely skip the radiation therapy that's normally provided prior to surgery, researchers reported at the American Societ...

    Opdivo Could Boost Outcomes for People Battling Hodgkin Lymphoma

    The widely used immunotherapy drug nivolumab (Opdivo) is safer and more effective in treating adults and children with advanced Hodgkin lymphoma than the targeted therapy now used as standard care is, new clinical trial results show.

    Nivolumab outperformed the drug brentuximab vedotin (Adcetris), extending progression-free survival by 94% at one year compared to 86%, said lead researcher ...

    What to Do When Tough-to-Treat Lymphoma Strikes During Pregnancy

    Not a lot is known about how physicians should handle cases in which a pregnant woman is diagnosed with relapsed/refractory lymphoma.

    A new study may provide some perspective.

    Though uncommon, this issue is still experienced by about one in 4,000 women, according to background notes with the study published June 1 in

  • Cara Murez HealthDay Reporter
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  • June 2, 2023
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  • Breakthrough CAR-T Cancer Treatments Are Boosting Patients' Quality of Life

    A therapy that bolsters the immune system may not only help certain cancer patients live longer, but better, a new study finds.

    The treatment, called chimeric antigen receptor (CAR) T-cell therapy, is used to fight certain types of blood cancer -- including leukemia and lymphoma -- that have not responded to standard treatments.

    It involves removing a patient's own immune system T-c...

    Jane Fonda Says Her Lymphoma Is in Remission

    Actress and two-time Academy Award winner Jane Fonda announced Thursday that her non-Hodgkin lymphoma is in remission.

    Fonda, 84, said in a blog post that she can quit chemotherapy treatments, calling it the "BEST BIRTHDAY PRESENT EVER!!!" Fonda, also a climate activist, will turn 85 on Wednesday.<...

    Race, Income Can Determine Blood Cancer Outcomes, Studies Show

    If someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.

    The ongoing impact of patient race and income to medical outcomes was in the spotlight Saturday in New Orleans at the annual meeting of the American Society of Hematology (ASH).

    In one study, a team led by

  • Ernie Mundell HealthDay Reporter
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  • December 12, 2022
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  • She Thought Cancer Had Won -- Until This Experimental Therapy

    The breast cancer of author and poet Stephanie Gangi has receded and advanced in wearying waves for two decades now.

    First diagnosed and treated in 1999, Gangi's cancer spread to the bone of her sternum in 2014. In 2021, a tumor the size of an orange appeared on her adrenal gland.

    "I could not possibly tell you the number of treatments I've been through,"said Gangi, 66, of New York ...

    FDA Warns of Rare Cases of Certain Cancers Linked to Breast Implants

    The U.S. Food and Drug Administration on Thursday warned doctors and their patients about rare cases of squamous cell carcinoma and various lymphomas developing in the scar tissue that forms around breast implants.

    Jane Fonda Has Non-Hodgkin Lymphoma

    Actress Jane Fonda has announced she has non-Hodgkin lymphoma.

    Fonda, 84, said she has started chemotherapy to fight the highly treatable cancer, calling herself very lucky because 80% of patients survive.

    Also known for her social activism, Fonda noted she has health insurance and access to the best doc...

    For Blood Cancer Patients, COVID Boosters Can Bring Some Immunity

    In a promising development, new research has discovered that most adults with blood cancers develop at least some immunity to COVID-19 after getting booster shots.

    "Our findings build on the wealth of literature showing that patients with

  • By Ellie Quinlan Houghtaling HealthDay Reporter
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  • July 11, 2022
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  • Ten Years After Gene Therapy for Leukemia, Doctors Say Patients Cured

    More than 10 years after Doug Olsen underwent an experimental gene therapy that turned his T-cells into cancer killers, his leukemia has vanished, University of Pennsylvania doctors report.

    "I'm doing great right now. I'm still very active. I wa...

    Many Cancer Patients Face Mounting Bills Despite Having Insurance

    Many insured cancer patients still experience serious money problems linked to their illness, new research affirms.

    For example, nearly 3 out of 4 insured patients with colon cancer have major financial hardship in the year after their diagnosis, which affects their social functioning and quality of life, according to

  • Steven Reinberg HealthDay Reporter
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  • January 4, 2022
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  • Many Blood Cancer Patients Get Little Protection From COVID Vaccine

    Anti-vaxxers felt their suspicions confirmed when former U.S. Secretary of State Colin Powell died from COVID-19 complications in mid-October despite being fully vaccinated.

    But Powell, 84, was being treated for blood cancer at the time of his death, and a new study reports that the COVID vaccines are producing little to no protection for some cancer patients.

    Nearly 3 out of 5 bloo...

    Cancer Care Costs U.S. $156 Billion Per Year; Drugs a Major Factor

    Private insurers paid out about $156.2 billion in 2018 for U.S. patients with the 15 most common cancers.

    Medication was the largest expense and drugs for breast, lung, lymphoma and colon cancers accounted for the largest chunk of those costs, according to a Penn State College of Medicine study.

    "The public often hears that the U.S. spends an inordinate amount of money on health car...

    Jeff Bridges Says Cancer Is in Remission, But COVID Fight Was Tougher

    Jeff Bridges has had a rough year.

    Almost a year ago, the actor was diagnosed with lymphoma. Then in January, he was exposed to the COVID-19 virus while receiving chemotherapy.

    "Covid kicked my (expletive) pretty good," Bridges wrote in a blog post on his website, USA Today reported.

    Bridges, 71, said he spent five weeks in the hospital with COVID-19 because his immun...

    Blood Cancer Patients Could Benefit From COVID Booster Shot: Study

    Patients with B-cell blood cancers who did not make antibodies to COVID-19 after two shots of vaccine may find that a third shot does the trick, new research finds.

    More than half the patients who had failed to respond to the first two shots had a positive response to the third, or booster, shot, according to the Leukemia & Lymphoma Society study.

    "The additional COVID-19 vaccine do...

    Mixed Progress Against Cancers in Teens, Young Adults

    There's some encouraging news for U.S. teens and young adults with cancer.

    Survival rates have improved for several types of cancer, though gains have been limited for some common kinds, according to a long-term study published online July 26 in the journal Cancer.

    The researchers used a wealth of accumulated data "to piece together a larger part of the cancer survival st...

    FDA Approves First Lymphoma Drug for Dogs

    The first full approval of a drug to treat lymphoma in dogs has been granted by the U.S. Food and Drug Administration.

    "While canine lymphoma affects fewer than 70,000 dogs in the U.S. annually, it accounts for up to 24% of all cancers in dogs, making it one of the most significant canine cancers," Steven Solomon, director of the FDA's Center for Veterinary Medicine, said in an agency new...

    Almost All Cancer Patients Respond Well to COVID-19 Vaccines

    Most cancer patients have a good immune response to COVID-19 mRNA vaccines, new research shows.

    Two of the three approved vaccines in the United States -- Pfizer and Moderna -- are mRNA vaccines.

    Researchers assessed 131 cancer patients and found that 94% developed antibodies to the new coronavirus three to four weeks after their second dose of a mRNA vaccine.

    Patients' median...

    Survivors' Plasma Helps Blood Cancer Patients Battle COVID-19

    Giving COVID-19 survivors' blood plasma to blood cancer patients hospitalized with COVID-19 significantly improves their chances of survival, a new study finds.

    "These results suggest that convalescent plasma may not only help COVID-19 patients with blood cancers whose immune systems are compromised, it may also help patients with other illnesses who have weakened antibody responses to th...

    COVID Vaccines Might Not Protect Certain Cancer Patients

    People with cancers of the blood, bone marrow or lymph nodes are at an increased risk of not making protective coronavirus antibodies after COVID-19 vaccination, a new study warns.

    The risk is particularly high for those with chronic lymphocytic leukemia (CLL). The researchers urged these patients and those who interact with them to get vaccinated but to keep wearing masks and practicing...

    Cancer Survivors at Higher Odds for Second Cancer: Study

    Cancer survivors are at greater risk of developing another cancer and dying from it, a new study finds.

    These new cancers can result from a genetic predisposition, from treatments such as radiation and chemotherapy used to fight the first cancer, as well as from unhealthy lifestyles such as smoking and obesity, according to researchers from the American Cancer Society.

    Some of these...

    Should Cancer Survivors Be Prioritized for COVID Vaccine?

    Cancer survivors have higher odds of dying from seasonal flu, suggesting they may also be at increased risk from COVID-19 and may need to be among the first in line for vaccination against both diseases.

    Researchers from the London School of Hygiene & Tropical Medicine analyzed medical data from more than 630,000 people in the United Kingdom between 1990 and 2014, including more than 10...

    Actor Jeff Bridges Shares Lymphoma Diagnosis

    Actor Jeff Bridges announced on Monday that he has been diagnosed with lymphoma.

    Telling his fans on Twitter, the acclaimed thespian said, "Although it is a serious disease, I feel fortunate that I have a great team of doctors and the prognosis is good. I'm starting treatment and will keep you posted on my recovery."

    According to the U.S. Centers for Disease Control and Prev...

    Almost 90,000 Young American Adults Will Get Cancer This Year: Report

    Nearly 90,000 Americans between 15 and 39 years of age will be diagnosed with cancer this year and more than 9,200 will die, a new report projects.

    One hematologist who deals with younger cancer patients said the shock of a diagnosis at this point in their lives can be overwhelming.

    "This population is unique, they're in the prime of their lives," said Dr. Tina Bhatnagar, w...

    Few U.S. Women Know About Cancer That Develops Near Breast Implants: Study

    There's a low level of awareness among American women about a form of lymphoma that can occur around breast implants, a new study finds.

    Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an immune system cancer. It's estimated to occur in between 1 in 3,000 and 1 in 12,000 women with textured breast implants. Smooth-surfaced implants are associated with a lower ra...

    Blood Test Could Spot 50 Different Cancers

    A simple blood test for dozens of cancers is in the works.

    Researchers say their test can detect more than 50 kinds of cancer at early stages and pinpoint their location in the body.

    "If these findings are validated, it will be feasible to consider how this test might be incorporated into a broader cancer screening strategy," said lead researcher Dr. Michael Seiden, preside...

    Health Risks Persist for Young Cancer Survivors

    Teen and young adult cancer survivors are nearly twice as likely to be hospitalized as those who haven't had cancer, a new study finds.

    "Few studies have investigated health risk in adolescents and young adults after cancer treatment," said study author Chelsea Anderson, a postdoctoral fellow at the American Cancer Society.

    She and her colleagues from the University of Utah ...

    Fewer Childhood Cancer Survivors Getting Hit by Heart Troubles

    Since the 1970s, serious heart disease among childhood cancer survivors had declined remarkably, a new study finds.

    The decline suggests that efforts to make cancer treatments, including radiation, less toxic are paying off, researchers say.

    For the study, researchers led by Dr. Daniel Mulrooney, from St. Jude Children's Research Hospital in Memphis, Tenn., collected data ...

    Regular Exercise Cuts Odds for 7 Major Cancers

    Exercise may reduce the odds you'll develop any of seven types of cancer -- and a new study suggests the more you exercise, the lower your risk.

    That's the conclusion of researchers who pooled data from nine published studies that included more than 750,000 men and women.

    "We found that the recommended amount of physical activity was in fact associated with significantly r...

    For Some, Follicular Lymphoma May Be Curable

    Some patients in remission from the blood cancer called follicular lymphoma can be considered cured, a new small study suggests.

    Using DNA sequencing, researchers were able to test the patients' blood to see if mutations that caused the cancer were still present two years after treatment. If these mutations aren't found, the patient can be given a clean bill of health, the study auth...

    New Study Finds a Family Risk for Blood Cancer

    If a close relative has had blood cancer, you're more likely to get it, a large new study reports.

    The researchers analyzed data from 16 million people in Sweden, including more than 153,000 diagnosed with blood cancer and more than 391,000 of their first-degree relatives: parents, siblings or children.

    Patients with a family link accounted for 4.1% of all blood cancer ...

    Breast Implants Tied to Rare Cancer Recalled

    Allergan's textured breast implants will be recalled due to their link to a rare cancer, the U.S. Food and Drug Administration announced Wednesday.

    Following a request from the FDA, the company will proceed with a worldwide recall of its Biocell textured breast implant products, the agency said.

    The recall stems from concerns about a tumor known as breast implant-associated ...

    New 'Cancer Vaccine' Attacks Tumors From Within

    A new method of brewing a cancer vaccine inside a patient's tumor could harness the power of the immune system to destroy the disease, researchers report.

    Immune stimulants are injected directly into a tumor, which teaches the immune system to recognize and destroy all similar cancer cells throughout the body, said senior researcher Dr. Joshua Brody. He is director of the Lymph...

    Baby Monkey May Offer Hope to Preserving Fertility of Kids With Cancer

    She's cute, and perhaps a medical breakthrough.

    Scientists say they have used frozen testicular tissue to achieve the birth of a healthy baby monkey named Grady -- a success they hope to eventually translate to childhood cancer survivors whose treatment has left them infertile.

    Infertility is a potential side effect of the chemotherapy and radiation used to treat various can...