Results for search "Sickle-Cell Anemia".
An exceptionally pricey gene therapy cure for sickle cell disease could soon be available, but it’s not clear whether insurance companies will balk at the cost and deny coverage.
On the surface, the gene therapy does not appear as cost-effective as the grinding medical care that sickle cell patients now receive, according to a new analysis.
Gene therapy applied just once to a sick...
While joint reconstruction surgeries are fairly common, they may be anything but routine for people with sickle cell disease.
Patients with the blood disorder who undergo total knee replacement are at a higher risk for complications than other patients, according to a new large-scale study.
“SCD patients undergoing total knee replacement need a multidisciplinary approach and ...
Too few children with sickle cell anemia are getting the recommended screening tests for stroke, a common complication of this disease, a new government report finds.
What's more, many aren't receiving
Folic acid, a B vitamin that's used widely to fortify foods and lower the risk of birth defects, may carry a hidden risk for those who have to take huge quantities of it: A new study shows those folks were more likely to get COVID-19 and to die from it.
“We examined whether COVID-19 diagnosis and death were related to the large doses of folic acid -- five times the safe upper limit -- p...
A network that receives and supplies blood for transfusions nationwide is calling for more diverse blood donors.
Less than 20% of blood donations are from people of color, but those donations are essential. Frequently transfused patients often require blood from donors with similar ethnic and racial backgrounds.
Those who need frequent transfusions include people with
Americans with sickle cell disease who have private insurance face average out-of-pocket costs of $1,300 a year and a lifetime total of $44,000, new research reveals.
That means that their out-of-pocket expenses are nearly four times higher compared to people without the inherited blood disorder, the
People with sickle cell disease who take corticosteroids to treat asthma or inflammation may suffer severe pain and even need to be hospitalized, researchers report.
This reaction to corticosteroids can be particularly severe among older people, women and patients not taking the drug hydroxyurea to treat their sickle cell symptoms. These were the most likely to be hospitalized, the study ...
A gene therapy that could provide a permanent cure for sickle cell disease continues to show success through a third wave of patients, researchers report.
The therapy, LentiGlobin, restored normal blood function in 35 sickle cell patients who had the one-time procedure, according to clinical trial findings published Dec. 12 in the
Treating sickle cell anemia with the drug hydroxyurea may also reverse related heart abnormalities, a new study suggests.
Heart issues are common among people with sickle cell disease. Among them are enlargement of the heart and an impaired ability to relax heart muscles, a condition called diastolic dysfunction that can lead to heart disease and heart failure and death. Long-term treatme...
People with sickle cell disease who have a history of severe pain episodes and coexisting organ conditions have an increased risk for severe COVID-19 illness, a new study suggests.
"This study tells us that all individuals with sickle cell disease are not at equal levels of risk," said study author Dr. Lana Mucalo, of the Medical College of Wisconsin. "Patients with a history of pain, as ...
It's been more than six months since Brandy Compton last landed in a hospital emergency room.
That's an amazing medical achievement, brought about by scientific breakthroughs that have been unfortunately overshadowed by the coronavirus pandemic, experts say.
Compton, 31, was born with sickle cell disease, a genetic condition that primarily affects people of African descent.
Researchers are using mice to study a potential new treatment that could help patients who have sickle cell disease, without some of the risks and side effects of existing therapies.
The investigators reported using genetic-based editing on mice to convert a disease-causing hemoglobin gene to a benign variant that would enable healthy blood cell production.
Sickle cell disease (SCD...
People with kidney failure related to sickle cell disease are less likely to receive a transplant than those without sickle cell disease, but it could be life-saving for them, a new study finds.
Sickle cell disease is a risk factor for kidney failure, and adults with sickle cell-related kidney failure who are on long-term dialysis have high rates of early death.
Kidney transplant is...
Sickle cell disease increases the risk of death or serious complications from COVID-19 infection, a pair of new studies suggests.
People with sickle cell disease -- a genetic blood disorder predominantly found in Black people -- are 6.2 times more likely to die from COVID-19 than the general Black population of the United States, one study found.
"Sickle cell disease patients should...
A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients' bone marrow cells, researchers report.
Both therapies work by switching on a gene that promotes production of fetal hemoglobin, said Dr. Lewis Hsu, chief medical officer of the Sickle Cell Disease Association of America.
Sickle cell dis...
People with sickle cell disease are at increased risk for severe complications from COVID-19, an expert says.
"Many patients experience a pain crisis, also known as a vaso-occlusive crisis, early in COVID-19 infection before respiratory symptoms develop," said Dr. Jennie Hart, clinical director of pediatric hematology/oncology at Herman and Walter Samuelson Children's Hospital at Sina...
Mild exercise is safe and beneficial for people with sickle cell disease, contrary to traditional beliefs, a new study finds.
Sickle cell disease affects blood flow in the body. Because strenuous exercise boosts blood flow, it can lead to heart problems and severe pain in someone with sickle cell. As a result, many patients are advised to avoid all types of exercise.
It is an annual rite of summer: sending young men out on football fields across America in the sweltering August heat for grueling practice sessions designed to prepare them for the coming season.
But a new study shows the ritual can be costly if players are pushed too hard. It is the most common way players die of non-traumatic injuries in high school and college football.
Pregnant women should keep in mind that donating their umbilical cord blood could save lives, a clinical cell therapy expert says.
Cord blood is the blood collected from the umbilical cord and placenta after the birth of a healthy baby, said Fabio Triolo. He is director of the Cellular Therapy Core laboratories at University of Texas Health Science Center at Houston.
An experimental drug for sickle cell disease reduced anemia and boosted the health of red blood cells in patients, according to a new study.
Whether the drug, voxelotor, will have long-term health benefits to patients remains to be seen.
But if approved for use by the U.S. Food and Drug Administration, "people living with sickle cell disease might have a new, once daily, tol...
People with severe pain from cancer or sickle cell anemia should not be denied coverage for opioid painkillers, a new clarification on federal guidelines states.
In the wake of the national opioid epidemic, various medical societies had encouraged doctors to rein in prescriptions for the powerful painkillers.
In 2016, the U.S. Centers for Disease Control and Prevention publi...
She's cute, and perhaps a medical breakthrough.
Scientists say they have used frozen testicular tissue to achieve the birth of a healthy baby monkey named Grady -- a success they hope to eventually translate to childhood cancer survivors whose treatment has left them infertile.
Infertility is a potential side effect of the chemotherapy and radiation used to treat various can...