Get Healthy!

Results for search "Genetics".

Health News Results - 178

Largest-Ever Study Ties Over 100 Genes to Autism

More than 100 genes appear to be involved in autism spectrum disorders (ASD), according to the largest genetic study of the condition to date.

The study, involving over 50 centers around the globe, identified 102 genes associated with ASD -- including a few dozen that had not been recognized before.

Some of the genes are also associated with intellectual disabilities and dev...

What Matters More for Obesity Risk, Genes or Lifestyle?

A new study suggests that genetics is not destiny when it comes to your odds of becoming obese.

For years, research into "obesity genes" has led many Americans to believe that their DNA makes becoming overweight and obese inevitable.

But the new study shows that daily lifestyle -- not genes -- probably plays the much bigger role.

The study tracked data on more tha...

Genes, Family Are Key Predictors of School Success

It may be possible to predict a child's chances of academic success at birth, a new study suggests.

Researchers found that kids' genes and their parents' education and wealth were big predictors of school success.

They analyzed data from 5,000 children born in the U.K. between 1994 and 1996, including test results at key stages of their education and their parents' wealth and ...

She Never Smoked -- And Got Lung Cancer in Her 40s

Nikki Moreno had spent nearly a year struggling for breath, and nothing seemed to help.

Not the inhalers, not the antibiotics and other drugs. Nothing seemed to help her breathe, and nothing got rid of her constant cough.

It finally got so bad that she landed in the emergency room at UCLA Medical Center in Santa Monica.

Moreno was not prepared for the series of sho...

'Designer Babies' a Long Way Off

"Designer babies" aren't going to be a reality anytime soon, researchers say.

Concerns about genetically altering embryos to have desired traits have been around nearly as long as in vitro fertilization (IVF) and the technology to screen embryos have existed.

But while recent live births resulting from embryonic CRISPR gene editing have re-focused attention on the issue, the...

'Don't Give Up:' Parents' Intuition Spots a Rare Illness Before Doctors Do

Parents usually know their child better than anyone, and if a parent suspects something is wrong, it probably is.

That was the case for Dan and Laura Wallenberg from Columbus, Ohio. EV Wallenberg was just 5 months old when they noticed that their daughter wasn't eating normally. They scheduled a visit with her pediatrician.

"I knew something wasn't right. But the doctor ju...

Gene Test Might Someday Gauge Your Cardiac Arrest Risk

Sudden cardiac death is terrifying because it's exactly that -- one minute you're fine and the next you're facing death, with no warning and no prior symptoms.

Now, new research shows the secret to who's at risk for cardiac arrest and who isn't could lie in people's genes. And a gene test might someday help predict who's most endangered, according to a study presented this weekend at ...

Exercise Can Help Prevent Depression, Even for Those at High Risk

Getting more exercise could help ward off depression, even if you have a genetic risk for it, new research shows.

For the study, researchers analyzed data from nearly 8,000 people and found that those with a genetic predisposition were more likely to be diagnosed with depression over the next two years.

But that was less likely for people who were more active at the study's ...

A Gene Kept One Woman From Developing Alzheimer's -- Could It Help Others?

Could one woman's rare genetic mutation one day have a global impact on dementia risk?

It's possible, say investigators who report on a potentially groundbreaking case of a woman whose genetic mutation staved off dementia for decades, even though her brain had already been damaged by Alzheimer's disease.

While most Alzheimer's cases are not driven by genetic predispo...

Many Cancer Docs Don't Discuss Costs of Pricey Gene Tests

Fighting cancer can be a long, hard battle, not to mention expensive. Now, new research shows that a quarter of oncologists don't discuss the cost of expensive tests with their patients.

Genomic tests on cancer cells can help determine which types of treatment might work, and which ones might not. However, such testing can be expensive, and not all tests and related treatments are cov...

Drug Trio Could Give Patients With Cystic Fibrosis a New Option

A three-drug combo that significantly improves lung function in cystic fibrosis patients could benefit 90% of people with the life-threatening disease, a new study suggests.

It included patients with a single copy of the most common genetic mutation for the disease.

Results of the international phase 3 clinical trial led the U.S. Food and Drug Administration to approve ...

FDA Approves New Drug for Most Common Form of Cystic Fibrosis

A new drug to treat most cystic fibrosis patients has been approved by the U.S. Food and Drug Administration.

Trikafta (elexacaftor/ivacaftor/tezacaftor) is the first triple combination therapy available to treat patients with the most common cystic fibrosis mutation. Its list price is $311,000 a year, same as one of the maker's earlier treatments for the genetic disease.

Tr...

Gene-Based Therapy Helps Fight Advanced Prostate Cancer

A drug that targets faulty gene repair may buy more time for some men with advanced prostate cancer, a new clinical trial finds.

Experts called the study "landmark," because it zeroed in on men with particular gene mutations that can be targeted with newer drug therapies. It's an approach that is already used in treating breast, ovarian and lung cancers.

Specifically, the tr...

Extinct Human Species Passed on Powerful Immune System Gene

You may have the extinct humans called Denisovans to thank for your adaptable immune system, Australian researchers suggest.

Denisovans were related to Neanderthals and interbred with modern humans about 50,000 years ago as modern humans left Africa for Papua New Guinea and Australia.

Modern humans got a gene variant from Denisovans that boosted immune reactions and inflamm...

Tiny Genetic Tweak May Stop Ebola Virus in Its Tracks

New experiments in monkeys suggest that one slight alteration to the DNA of the Ebola virus might render it harmless to humans.

Changing just a single protein appears to activate the body's immune system to fight off the deadly infection, researchers report.

The mutated virus also acts like a vaccine that protects the animals from becoming infected, they added.

For...

How Your Genes Affect the Number on Your Scale

Could your genes be keeping you from losing weight?

While you shouldn't use a family tendency toward wide hips or an apple shape as an excuse to stray from a healthy diet, acceptance can help you reassess your personal ideal and make you happier with your body.

Hundreds of genes have been linked to weight. Some affect where fat is distributed on your body while others impac...

Kids in Poor Neighborhoods Face Higher Odds for Obesity as Adults

Growing up in a poor neighborhood significantly increases kids' odds of becoming obese adults, and the risk is highest among teens, a new study says.

It found that children from poor neighborhoods had 31% higher odds for adult obesity, and the risk was much higher (29%) among 11- to 18-year-olds than for younger children (13%).

"Growing up in a disadvantaged neig...

Scientists ID Genes Tied to Left-Handedness

For the first time, scientists have found four spots on your DNA that might determine whether you wield your pen with your left hand.

Of the four gene regions, three are associated with proteins involved in brain development and structure, according to a genetic analysis of about 400,000 people in the United Kingdom, including more than 38,000 left-handers.

The study also fo...

Even Small Improvements in Cholesterol, Blood Pressure Help Prevent Heart Attack

Small, lasting changes in cholesterol and blood pressure levels can dramatically reduce the risk of heart disease and strokes over a lifetime, new research suggests.

The large study found that a combination of a drop in LDL cholesterol (the bad type) of 14 mg/dL and a 5 mm Hg drop in systolic blood pressure (the top number in a blood pressure reading) cut the lifetime risk of heart di...

Lifestyle May Matter More Than Your Genes in Early Heart Disease

An unhealthy lifestyle is a bigger contributor to heart disease than genetics for many younger adults, according to a new study.

The findings show that good health habits should be a key part of prevention efforts, even in people with a family history of early heart disease, researchers said.

The study included 1,075 people under age 50. Of those,...

There Is No 'Gay Gene,' Major Study Concludes

There's no such thing as a single "gay gene" that drives a person's sexual behavior, concludes the largest genetic study ever conducted on the issue.

Instead, a person's attraction to those of the same sex is shaped by a complex mix of genetic and environmental influences, similar to what's seen in most other human traits, researchers report.

"This is a natural and normal pa...

Staying Optimistic Might Lengthen Your Life, Study Shows

An upbeat view of life may increase your odds for living to a ripe old age, new research suggests.

The finding stems from a look at optimism and longevity among nearly 70,000 women and 1,400 men. It builds on earlier research linking higher levels of optimism to lower risks of chronic illness and premature death.

"This study took us further by suggesting that optimistic peo...

Dodge Dementia With Healthy Lifestyle

Seniors, here's a recipe for preventing dementia: eat well, exercise and don't smoke.

The only catch, according to a new study? If you carry genes that leave you vulnerable to the memory-robbing disease, lifestyle might not be enough.

In the study, researchers found that of over 6,300 adults aged 55 and older, those with healthy habits had a lower risk of being diagnosed wit...

U.S. Task Force Updates Breast Cancer Gene Testing Recommendations

Mutations in two genes -- BRCA1 and BRCA2 -- are known to significantly increase the risk of breast cancer, but experts have long debated which women should be tested for them.

New recommendations from the U.S. Preventive Services Task Force (USPSTF) may help clarify who can benefit most from a risk assessment test. Now, if a woman has a high risk, the task force is recommending that...

'Dr. Google' Helps Some Patients Diagnose a Rare Disease

A middle-aged woman had persistent symptoms that doctors couldn't explain. Frustrated, she took an increasingly common route: a search through the internet.

"Dr. Google" led the woman to specialists at Wake Forest University Medical Center in Winston-Salem, N.C. There, she was diagnosed with a rare genetic condition called autosomal dominant tubulointerstit...

Scientists Creating Gene Map of Human 'Microbiome'

The number of genes in bacteria that live in and on people could top 1 billion trillion -- and at least half appear to be unique to their host.

That mindboggling math comes from scientists at Harvard Medical School and Joslin Diabetes Center in Boston who have set out to map all genes of the human microbiome.

The research could reveal links between microbiome genes and human...

Scientists Uncover More Autism Genes

In a finding that underscores the major role genetics plays in autism risk, researchers report they have identified 16 new genes linked to the developmental disorder.

The investigators conducted genetic analyses of 2,300 people from nearly 500 families with at least two children with autism. Of the children in the study, 960 had autism and 217 did not.

The researchers pinpoi...

New Study Finds a Family Risk for Blood Cancer

If a close relative has had blood cancer, you're more likely to get it, a large new study reports.

The researchers analyzed data from 16 million people in Sweden, including more than 153,000 diagnosed with blood cancer and more than 391,000 of their first-degree relatives: parents, siblings or children.

Patients with a family link accounted for 4.1% of all blood cancer ...

Hair Loss Not Just a Male Problem

The sad sight of a receding hairline is not limited to men, a dermatologist says.

Hair loss is just as common in women, and it can occur due to factors such as genetics, and the hairstyles and hair products used by women.

It's important to identify the cause of hair loss in women to treat it, said dermatologist Dr. Paradi Mirmirani.

"Making sure you have the right...

One Gene Change 2 Million Years Ago Left Humans Vulnerable to Heart Attack

As far as scientists know, humans are the only species that get heart attacks linked to clogged arteries.

Now, new research suggests that just one DNA change occurring 2 to 3 million years ago may be to blame.

The finding might give insight into how to prevent and treat the attacks, according to researchers at the University of California, San Diego (UCSD). Already, they say...

Autism Largely Caused by Genetics, Not Environment: Study

The largest study of its kind, involving more than 2 million people across five countries, finds that autism spectrum disorders are 80% reliant on inherited genes.

That means that environmental causes are responsible for just 20% of the risk.

The findings could open new doors to research into the genetic causes of autism, which the U.S. Centers for Disease Control an...

Evolution Could Explain Why Staying Slim Is So Tough

It's not easy maintaining a healthy weight. Even when you manage to drop a few pounds, they often return.

Why would the body seem to encourage obesity?

New research suggests the answer lies far back in human evolution, with an anti-starvation mechanism that primes the body to store fat.

The key to this mechanism is a protein dubbed "RAGE," according to New York Un...

How to Protect Your DNA for Big Health Benefits

You might think that stress affects you only emotionally or that a lack of sleep simply leaves you feeling cranky. But these are among the many lifestyle factors that can lead to health problems because of changes that they cause within your body's cells.

Packed inside every cell is your DNA and its strands of chromosomes. Chromosomes are protected, top and bottom, by sections called ...

Alzheimer's Genes Might Show Effects in Your 20s

Every college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzheimer's disease have memory lapses, it could be an early sign of something serious.

That's the concern raised by a new memory test taken by nearly 60,000 men and women between the ages of 18 and 85.

...

AHA News: Genetics May Help Predict the Right Blood Pressure Drug for You

Medication can play a huge role in reducing high blood pressure, a leading cause of stroke, heart attack and other serious health problems. Yet given the wide selection of drugs for doctors to choose from, figuring out which drug works best for someone is difficult.

But researchers may have found a better way to predict the effectiveness and side effects of blood pressure drugs, and ...

How Do Birth Defects Affect Childhood Cancer Risk?

Children with birth defects may be at increased risk for childhood cancer, a new study finds.

Researchers analyzed data from more than 10 million children born in Texas, Arkansas, Michigan and North Carolina between 1992 and 2013.

Compared to children without a birth defect, those with genetic defects were almost 12 times more likely to develop cancer by age 18. Those whose ...

Many Advanced Colon Cancers Were 'Born' Ready to Spread

In most patients with metastatic colon cancer, the disease may have begun spreading throughout the body very early on -- when the original tumor was no bigger than a poppy seed, a new study suggests.

Metastatic refers to the most advanced stage of cancer, when the original tumor has spread to distant sites in the body.

Traditionally, that's been seen as a "late" event -- the...

Your Mom Plays a Role in Age at Menopause, Longevity

For women, predicting when they'll reach menopause is anyone's guess. But if you want to get some foresight, you should ask your mother.

For most women, menopause begins at around 52. But for thousands of women it starts much later, and for some, a lot earlier. Those whose menopause starts later may also be looking at a longer life expectancy, researchers have found.

Smoking...

Gene Test Might Someday Gauge Your Heart Attack Risk

Can a DNA test predict a person's future heart health? Perhaps, researchers say.

A team of Canadian researchers found that by analyzing a person's entire genome, it might be possible to predict their future heart disease risk.

The so-called "polygenic risk score" analysis looks for key heart disease indicators -- genetic "biomarkers" -- along with an individual's entire g...

How Chinese Gene-Editing Could Backfire: Babies Might Have Shorter Lives

Last year, a scientist from China created a storm of controversy when he claimed he'd used gene-editing technology to create "designer" twin babies. Now, a new study is highlighting one of the dangers of that endeavor.

Researchers have found that the gene mutation the scientist used -- affecting a gene called CCR5 -- is associated with a shorter life span: People who carry two copies ...

Your Gut Bacteria Could Affect Your Response to Meds

Ever wonder why a drug that works for someone else doesn't seem to work for you? You might want to check your gut for the answer.

Gut bacteria that process more than 150 medicines have been pinpointed by researchers, who also identified genes that give the bacteria this ability.

The findings underline the role gut bacteria play in how well people respond to medications, acco...

Blood Test Could Spot Multiple Cancer Types, Researchers Say

A gene-based blood test can accurately detect breast, colorectal, lung, ovarian, pancreatic, gastric or bile duct cancers in patients, researchers report.

The test uses artificial intelligence to identify and interpret "fragments" of DNA in the blood that indicate the presence of cancer, explained researchers led by Dr. Victor Velculescu. He helps direct the Cancer Biology Program at ...

Do You Have the 'Fainting Gene'?

Some folks are more prone to fainting than others, and the reason might lie in their DNA.

Danish researchers who analyzed millions of gene variants in DNA of 400,000 people have zeroed in on a gene that increases a person's risk for fainting.

It's believed that 20% to 30% of people faint at least once in their lifetime, often due to heat, dehydration or anxiety. But ...

New Gene Variants for Type 2 Diabetes Found

It has long been known that lifestyle affects a person's risk of developing type 2 diabetes. Now, researchers report that they have identified rare variants of four genes that may also play a part.

For the study, an international team of scientists analyzed protein-coding genes from nearly 21,000 people with type 2 diabetes and 25,000 people without diabetes across a range of ethnici...

Your DNA Might Determine Whether You're a Dog Lover

Could a love for canines be contained in your genes?

New research from Europe suggests that's so after comparing the genetic makeup of more than 35,000 twin pairs with dog ownership. The researchers concluded that genetic variations explained more than half of the likelihood of having a dog.

"We were surprised to see that a person's genetic makeup appears to be a significant...

About 1 in 1,000 Babies Born 'Intersex,' Study Finds

Cases in which a newborn's genitals make it unclear whether the child is a boy or girl may be more common than once believed, researchers say.

One example of what's known as ambiguous genitalia is a baby girl with an enlarged clitoris that looks more like a small penis, the study authors explained.

In some cases, infants have external sex organs that don't match their intern...

Device Spots Lymphedema Early in Breast Cancer Patients, to Help Stop It

An easy-to-use, noninvasive device can detect early signs of the cancer complication known as lymphedema, a new study reports.

Lymphedema is the buildup of fluid in the body's tissues when a part of the lymph system is damaged, as can happen in cancer care, according to the U.S. National Cancer Institute (NCI).

The fluid causes swelling, usually in the arms or legs, and can b...

Male-Hormone Gene May Help Cause Polycystic Ovary Syndrome

Polycystic ovary syndrome is a common cause of infertility and type 2 diabetes, but little is known about its origins. Now, new research suggests a gene involved in male hormone production plays a big role in the disorder's development.

"We're starting to make headway on what causes PCOS [polycystic ovary syndrome]. It's very frustrating for patients because it's poorly understood," ...

Will You Get Fat? Genetic Test May Tell

As obesity becomes epidemic among Americans, many could over- or underestimate their odds for piling on the pounds. But a new genetic "score" might take the guesswork out of all of that, researchers say.

Using information on more than 2 million gene variants linked to body weight, the scientists created a so-called polygenic score that may help quantify a person's obesity risk.

...

Poverty Could Leave Its Mark on Genes

Poverty may influence how genes function, researchers report.

Specifically, they found that poverty is associated with levels of DNA methylation -- which can shape gene expression -- in nearly 10% of genes.

The findings are significant for a number of reasons, the researchers said.

"First, we have known for a long time that [poverty] is a powerful determinant o...