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Experimental Drug Works Quickly on Major Depression

WEDNESDAY, Sept. 4, 2019 (HealthDay News) -- Antidepressants typically take four to eight weeks to ease the debilitating symptoms of depression, but an early clinical trial found a new type of drug brought relief in just two weeks.

"SAGE-217, once fully developed, has potential to offer relatively quick and clinically meaningful alleviation of depressive symptoms in patients with mode...

What Treatments Work Best to Prevent Suicide?

TUESDAY, Aug. 27, 2019 (HealthDay News) -- If you or someone you love is thinking about suicide, a new review points to effective treatments that can reduce suicide risk.

Some involve therapy -- cognitive behavioral therapy (CBT) or dialectical behavior therapy (DBT) -- while others involve medication, such as ketamine (by infusion) or lithium.

"People should be aware that ther...

Easing Depression Can Bring Longer Life to People With Diabetes

WEDNESDAY, July 3, 2019 (HealthDay News) -- Treating depression may have an added benefit for people with diabetes -- longer life.

A large new study from Taiwan found that antidepressants cut the risk of dying during the study period by more than one-third for people with diabetes and depression.

"The first nationwide population-based study showed antidepressant use was as...

FDA Poised to Approve Ketamine-Like Drug to Ease Depression

TUESDAY, March 5, 2019 (HealthDay News) -- The U.S. Food and Drug Administration could give its approval this week to esketamine -- a relative of the "club drug" and anesthetic ketamine -- against severe depression.

If that approval comes, it could be the first new class of medicines approved for years against an illness that plagues millions of Americans.

Approval couldn't ...

PTSD Drug May Do More Harm Than Good

THURSDAY, Dec. 27, 2018 (HealthDay News) -- A drug used to treat post-traumatic stress disorder (PTSD) may actually be harmful, a new study suggests.

The high blood pressure drug prazosin is sometimes used to treat PTSD-related nightmares and insomnia that can increase suicide risk. But this small study suggests the drug may make nightmares and insomnia worse and not reduce suicidal t...

Many Say Ketamine Eased Their Depression, But Is It Safe?

WEDNESDAY, Dec. 19, 2018 (HealthDay News) -- Jen Godfrey couldn't shake the "deep cloud" that lingered even after she found an antidepressant she could tolerate.

Then a string of stressors hit -- five years of fertility treatment and an 80-pound weight gain during pregnancy that left her with persistent pain; a close relative's suicide; another who went missing; and her own divorce. I...

Brexit Had Brits Turning to Antidepressants: Study

MONDAY, Dec. 3, 2018 (HealthDay News) -- An increase in prescriptions for antidepressants followed the 2016 "Brexit" vote in England, a new study reports.

This increase may have stemmed from increased uncertainty in some people following the unexpected vote in favor of the United Kingdom leaving the European Union, according to the researchers.

For the study, the researcher...

Opioid Addicts Turning to Unapproved Antidepressant to Get High

THURSDAY, Aug. 2, 2018 (HealthDay News) -- In a trend that suggests opioid addicts are turning to new fixes, a government report shows that use of an unapproved antidepressant is becoming more widespread in the United States.

Tianeptine is used in some European, Asian and Latin American countries for treatment of depression and anxiety. But the U.S. Food and Drug Administration has n...

Treating Depression May Prevent Repeat Heart Attack

TUESDAY, July 24, 2018 (HealthDay News) -- It's common for heart attack survivors to develop depression. Now a new trial has found that antidepressant treatment may help those patients avoid a second heart attack.

The study, of 300 heart patients with depression, found that treatment with the antidepressant escitalopram (Lexapro) almost halved the risk of suffering another heart attac...

Could Antidepressants During Pregnancy Slow a Child's Motor Skills?

THURSDAY, June 21, 2018 (HealthDay News) -- Babies exposed to antidepressants during their mother's pregnancy may face a slightly higher chance of having problems with their motor skills, a new review suggests.

But the Australian researchers cautioned that more research is needed before firm conclusions can be made, since the studies they analyzed varied widely in the way they were ca...

Study Affirms What Many Know: Antidepressants May Lead to Weight Gain

THURSDAY, May 24, 2018 (HealthDay News) -- If you're taking an antidepressant, you're likely to gain weight, a new study out of Britain reports.

That's a finding that generated little surprise among mental health experts.

"Psychiatrists have known about it, written about it and heard their patients talk about it for decades," said Dr. Brian Keefe, a psychiatrist and medical ...

Could Mom-to-Be's Antidepressants Have an Upside for Baby's Brain?

MONDAY, May 7, 2018 (HealthDay News) -- Children who were exposed to antidepressants in the womb may score higher on certain tests of mental abilities at the age of 12, a small, preliminary study suggests.

Among the 51 kids the researchers analyzed, those whose mothers used antidepressants during pregnancy typically scored higher on tests of "executive function" than kids with no pren...

Common Antidepressants in Pregnancy May Alter Fetal Brain Development

MONDAY, April 9, 2018 (HealthDay News) -- Pregnant women who take certain antidepressants may unknowingly compromise the brain development of their child, researchers suggest.

The concern is based on a new analysis of brain scans involving nearly 100 newborns, some of whom were born to mothers who took selective serotonin reuptake inhibitors (SSRIs) while pregnant. Some examples of SS...

Antidepressants Do Work, Some Better Than Others: Study

THURSDAY, Feb. 22, 2018 (HealthDay News) -- Antidepressant drugs actually do help ease depression, countering debate over whether the medications do what they're supposed to, a large research review has found.

Some antidepressants, though, are more effective and better tolerated than others, the findings showed.

The researchers analyzed data from 522 trials -- published and ...

Mom-to-Be's Antidepressants Tied to Kids' Psychiatric Woes

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Children whose mothers took antidepressants during pregnancy may be at increased risk for psychiatric disorders themselves, a new study suggests.

Researchers reviewed data from more than 905,000 children born in Denmark between 1998 and 2012. The children's health was followed for up to 16.5 years. During the follow-up period, 32,400 of the ...