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Therapeutic Cancer Vaccine Shows Promise Against Multiple Tumor Types

Marc Baum went through all the usual steps to treat his bladder cancer -- a couple of surgeries, radiation therapy and chemotherapy, all in a three-month period.

But doctors hope that an extra step -- an experimental vaccine -- will be what keeps Baum's cancer from coming back.

A vaccine that uses genetics to teach a person's immune system how to precisely target the cancer has prov...

The Future of Cancer for Americans

At first glance, it appears that little will change between now and 2040 when it comes to the types of cancers that people develop and that kill them, a new forecast shows.

Breast, melanoma, lung and colon cancers are expected to be the most common types of cancers in the United States, and patients die most often from lung, pancreatic, liver and colorectal cancers, according to the lates...

Why So Many New Cancer Diagnoses When Americans Turn 65?

A few years ago, Dr. Joseph Shrager, a professor of cardiothoracic surgery at Stanford University School of Medicine, noticed that lung cancer diagnoses were noticeably higher at age 65 than at slightly older or younger ages.

"There was no reason rates should differ much between the ages of 63 and 65," Shrager said.

He discussed this with his colleagues, who said they were seeing so...

Obesity Tied to Shorter Survival in Cancer Patients

Obesity may shorten the lives of patients with certain types of cancers, but not others, a new research review concludes.

The analysis, of more than 200 studies, found that across numerous cancers, obesity was linked to shorter survival. The list included breast, colon, prostate, uterine and pancreatic cancers.

On the other hand, patients with lung, kidney or melanoma skin cancer al...

Nitrogen Dioxide, a Car Exhaust Pollutant, Is Raising Death Rates: Study

Even small increases of nitrogen dioxide (NO2) air pollution may cause an uptick in heart- and lung-related deaths, underscoring the need to tighten limits on this type of air pollution, Chinese researchers say.

NO2 is produced by burning fuel for vehicles, power and industrial production. World Health Organization (WHO) air quality guidelines recommend NO2 levels not exceed an annual ave...

More Americans Would Get Lung Cancer Screening Under New Guidelines

The number of Americans recommended for routine CT scans to spot lung cancer just got a lot bigger.

People between the ages of 50 and 80 who don't have symptoms of lung cancer, but are at high risk for the disease due to their smoking history should have the annual screen to help detect the disease early, the U.S. Preventive Services Task Force (USPSTF) concluded in new recommendations r...

Wildfire Smoke Is Especially Toxic to Lungs, Study Shows

Fine particles in wildfire smoke pose a far greater threat to the lungs than similar particles in vehicle exhaust and other types of air pollution, researchers report.

These fine particles -- called PM2.5 -- have a diameter about 1/20th the size of a human hair and can get into the respiratory tract, enter the bloodstream and damage key organs.

PM2.5 is the main component of wildfir...

Breast Cancer Surpasses Lung Cancer as Leading Cancer Diagnosis Worldwide

Breast cancer has surpassed lung cancer as the world's most commonly diagnosed cancer.

In 2020, there were an estimated 19.3 million new cancer cases and nearly 10 million cancer deaths worldwide, according to the Global Cancer Statistics 2020 report from the American Cancer Society (ACS) and the International Agency for Research on Cancer.

Overall, 1 in 5 people get cancer during t...

Segregation, Poverty Tied to Worse Outcomes for Black Lung Cancer Patients

Racial segregation may help explain why Black Americans with lung cancer do more poorly than their white counterparts, a new study suggests.

For years, U.S. studies have documented racial disparities in lung cancer. Black Americans are less likely to receive surgery for early-stage lung cancer -- the standard of care -- and they typically die sooner.

The reasons, however, are not fu...

How Smoking Could Help Spur Breast Cancer's Spread

Here's one reason why past or current smoking may handicap you if you are battling breast cancer: New research suggests that nicotine promotes the spread of the disease to your lungs.

Smoking is known to increase the risk that breast cancer will spread, which lowers the survival rate by one-third at diagnosis. But the role of nicotine in the spread of breast cancer to the lungs has been l...

Fewer U.S. Cancer Patients Are Dying From Suicide, Study Finds

New research reveals an encouraging trend: Despite the rate of suicide rising overall for Americans, U.S. cancer patients are actually less likely now to take their own life than in the past.

Researchers at the American Cancer Society (ACS) tracked national data on causes of death among Americans for the years 1999 through 2018. They found "a decreasing trend of cancer-related suicide du...

Cancer Screening Fell Sharply Early in Pandemic, But Has Rebounded

As clinics closed for non-essential care and patients' COVID-19 fears kept them from check-ups, the United States saw a steep drop in cancer screenings and diagnoses during the first peak of the pandemic, a new report finds.

Researchers analyzed data on how many patients underwent cancer screening tests -- procedures such as mammograms, colonoscopies, Pap tests, PSA blood tests for prosta...

U.S. Cancer Death Rates Keep Falling: Report

Improved lung cancer treatment is a major reason for the 31% decline in cancer death rates in the United States between 1991 and 2018, including a record 2.4% decrease from 2017 to 2018, the American Cancer Society says.

How the COVID-19 pandemic will affect this downward trend is unknown, the society noted.

"The impact of COVID-19 on cancer diagnoses and outcomes at the population ...

Women May Transmit Cancer to Infants in Childbirth, Reports Suggest

WEDNESDAY, Jan. 6, 2021 -- In extremely rare instances, newborns can contract cancer from their pregnant moms during delivery, a new case report suggests.

Two boys, a 23-month-old and a 6-year-old, developed lung cancers that proved an exact genetic match to cervical cancers within their mothers at the time of birth, Japanese researchers report.

It appears that the boys breathed in ...

Cancer Survivors at Higher Odds for Second Cancer: Study

Cancer survivors are at greater risk of developing another cancer and dying from it, a new study finds.

These new cancers can result from a genetic predisposition, from treatments such as radiation and chemotherapy used to fight the first cancer, as well as from unhealthy lifestyles such as smoking and obesity, according to researchers from the American Cancer Society.

Some of these...

Pandemic Closures, Fears Keep Patients From Lung Cancer Screening

When the COVID-19 pandemic hit the United States, many routine cancer screenings were put on hold. Now a new study suggests that lung cancer screenings have yet to rebound.

The findings come from one hospital system, but experts said they add to worries about the pandemic's impact on cancer care.

In the spring, when many U.S. hospitals were overrun with COVID-19 patients and stay-at...

Some Talc Products Contain Asbestos: Study

Nearly 15% of talc-based cosmetic products analyzed in a recent study contained asbestos.

Environmental Working Group (EWG) -- an American advocacy nonprofit that commissioned the tests and did the analysis -- said methods used by the cosmetics industry to screen talc supplies are inadequate. The voluntary testing method developed by industry is not sensitive enough to screen for asbestos...

Women More Likely to Survive Lung Cancer After Surgery: Study

Women have higher survival rates after lung cancer surgery than men, according to a new study.

Previous research on sex differences in survival after lung cancer treatment has yielded conflicting results, so researchers at the Karolinska Institute in Sweden decided to study the association between gender and survival after lung cancer surgery.

"The health care sector is always striv...

Black Cancer Survivors Often Face Added Challenges: Study

Social and financial struggles are common among Black American cancer survivors and take a heavy toll on their health-related quality of life, according to a new study.

Health-related quality of life among cancer survivors -- how a person perceives their mental, physical and social well-being -- tends to be significantly lower among Black Americans than in other groups.

In this stud...

Lung's Microbiome Might Play Role in Cancer

Lung cancer patients who harbor certain bacteria in the airways may have a poorer prognosis, a new study finds, adding to evidence that the body's "microbiome" may play a role in cancer patients' outlook.

The microbiome refers to the trillions of bacteria and other microbes that naturally dwell in the body. Research in recent years has been revealing how important those bugs are to the bo...

Obamacare Cut Death Rates for 3 Major Cancers

Expanded Medicaid passed in some states as part of the Affordable Care Act has significantly reduced deaths from newly diagnosed breast, lung and colon cancers, a new study finds.

Death rates from these cancers are lower in states that opted for expanded Medicaid than in those that didn't. The positive trend is largely due to earlier diagnosis, which increases the odds of survival, t...

Immunotherapy Drug Boosts Survival for Lung Cancer Patients

A newly approved drug for the leading form of the number one cancer killer, lung cancer, does improve patient survival, a new study confirms.

The immunotherapy drug Tecentriq (atezolizumab) was approved earlier this year by the U.S. Food and Drug Administration to treat patients with newly diagnosed non-small cell lung cancers (NSCLC), which comprise up to 85% of all lung tumors.<...

No Link Found Between Blood Pressure Meds and Cancer: Study

Blood pressure drugs don't increase the risk of cancer, according to the largest study to examine the issue.

A possible link between blood pressure drugs and cancer has been the subject of debate for decades, but evidence has been inconsistent and conflicting.

For this study, researchers analyzed data from 31 clinical trials of blood pressure drugs that involved 260,000 peop...

Even 'Social Smokers' Up Their Odds of Death From Lung Disease

Even light smokers are much more likely to die of lung disease or lung cancer than nonsmokers, a new study warns.

"Everyone knows that smoking is bad for you, but it's easy to assume that if you only smoke a little, the risks won't be too high," said study co-leader Pallavi Balte, of Columbia University Irving Medical Center, in New York City.

The new study shows how wrong ...

Better Treatments Bring Better Survival After Lung Cancer

Fewer Americans have been dying of lung cancer in recent years -- partly because of advances in treatment, a new government study finds.

The researchers found that after a gradual decline, lung cancer deaths in the United States started to drop more quickly in 2013. That coincided with the introduction of new "targeted" drugs that can more precisely go after certain lung tumors.

...

Cancer Diagnoses Plunge as Americans Avoid Screening During Pandemic

As COVID-19 continues to impact nearly all aspects of American health care, researchers warn that the United States has seen a troubling drop in cancer diagnoses since the pandemic began.

The drop is not being attributed to a downturn in cancer incidence, but rather a COVID-driven reluctance to get screened.

"Our research found that during the COVID-19 pandemic, between Marc...

Blood Test Might Spot Cancer Years Earlier

Scientists are working on a blood test that may catch five common cancers years sooner than current methods.

The blood test, which is still experimental, hunts for certain genetic "signatures" associated with tumors. Researchers found that it can detect five types of cancer -- colon, esophageal, liver, lung and stomach -- up to four years earlier, compared to routine medical care.

...

Get on the Bus: Lifesaving Lung Screens Hit the Road

Irene Johnson noticed a big, blue bus bearing the words "Breathe Easy" outside the Benton, Tenn., library during the 2019 Labor Day weekend.

Inside, a librarian told Johnson that the bus was a mobile CT unit that travels around screening smokers for lung cancer.

Former longtime smokers, both Johnson and her husband, Karl, fit the criteria for getting screened, so they decide...

New Guidelines Could Double Number Eligible for Lung Cancer Screening

CT scans have been proven to help spot lung cancer early and save lives. Now, updated expert recommendations could double the number of Americans who are eligible for the yearly screening.

The recommendations -- from the U.S. Preventive Services Task Force (USPSTF) -- would expand the definition of "high risk" for lung cancer. That's expected to not only increase the number of people ...

There's No Healthy Alternative to Smoking Except Quitting: Study

Smoking is terrible for your heart and lungs, and simply switching to e-cigarettes won't do much good, a major new analysis finds.

That's especially true now amid the COVID-19 pandemic, experts added.

The only truly healthy way out for nicotine addicts is quitting, said a team led by Thomas Münzel, a cardiologist at University Medical Center in Mainz, Germany. His team...

Drug Could Boost Survival From Lung Cancer Affecting Non-Smokers

MONDAY, June 1, 2020 (HealthDay News) -- The drug Tagrisso could offer hope to patients battling a form of lung cancer that typically hits people with little or no history of smoking, a new trial finds.

Taken after surgery to remove the lung tumor, Tagrisso (osimertinib) greatly extended the average survival of people battling a non-metastatic form of non-small cell lung cancer (NSCL...

Tumors Have Their Own Bacterial Colonies That Could Guide Cancer Care

The human body is teeming with bacteria, and a new study finds the same is true of many cancers -- raising questions about what role microbes might play in the diseases.

Researchers have already known that tumors in certain areas of the body -- like the gut -- harbor bacteria of their own. But the new research reveals that a range of cancers, including those of the breast, lungs, bone...

In Nonsmokers, COPD May Up Lung Cancer Risk

Nonsmokers with chronic obstructive pulmonary disease (COPD) have a greater risk for lung cancer, a new study indicates.

In fact, their risk is similar to that of smokers without chronic lung disease, researchers found.

COPD includes respiratory conditions that narrow the airways, such as bronchitis and emphysema. Smoking is the leading cause of both COPD and lung cancer.

Blood Test Could Spot 50 Different Cancers

A simple blood test for dozens of cancers is in the works.

Researchers say their test can detect more than 50 kinds of cancer at early stages and pinpoint their location in the body.

"If these findings are validated, it will be feasible to consider how this test might be incorporated into a broader cancer screening strategy," said lead researcher Dr. Michael Seiden, preside...

COVID-19 May Force Some Cancer Patients to Delay Treatment

Early findings involving cancer patients from Wuhan, China -- the original epicenter of the COVID-19 pandemic -- suggest that many contracted the coronavirus while undergoing treatment in the hospital.

That could mean that this vulnerable population might need to discuss delaying cancer care to help minimize their odds of infection, the study authors said.

"We propose that a...

U.S. Sees Big Drop in Deaths From Melanoma

New treatments for melanoma have dramatically reduced deaths from this often fatal skin cancer.

Leaders of a new study report that the death rate from aggressive melanoma that spread to other organs plummeted 18% between 2013 and 2016, after jumping 7.5% between 1986 and 2013. The figures apply to white Americans, the group that accounts for nearly all cases of melanoma in th...

Certain Cancers Linked to Higher A-Fib Risk, Study Finds

People with a history of certain cancers have more than double the risk for the heart rhythm disorder atrial fibrillation, a new study says.

A-fib is a common disorder that can lead to palpitations, dizziness and fatigue. Untreated, it can cause blood clots, stroke and heart failure, and people with a-fib have five times the risk of stroke than other people.

"When we looked ...

Minorities Less Likely to Get Recommended Lung Cancer Imaging

Black and Hispanic Americans are less likely than whites to receive recommended lung cancer imaging, a new study claims.

PET-CT imaging is recommended because it provides doctors the best possible picture of non-small cell lung cancer (NSCLC), which helps determine the best treatment for the patient.

The University of Colorado Cancer Center study examined PET-CT use and outc...

Low-Dose Chest Scans Don't Appear to Harm DNA

Low-dose chest CT scans don't appear to damage human DNA, a new study shows.

The U.S.-based National Lung Screening Trial, conducted between 2002 and 2010 and involving more than 53,000 heavy and former smokers, revealed that these chest scans can significantly cut lung cancer deaths compared to chest X-rays. They do so by finding cancers at an earlier stage, researchers explained.

For Black Americans, Exercise Brings Real Boost to Life After Cancer

Regular exercise can benefit black cancer survivors' physical and mental health, but most don't get the recommended amount of activity, a new study says.

Cancer survivors should get at least 150 minutes of moderate to vigorous physical activity a week, according to the American Cancer Society (ACS).

For most cancers, black patients have a higher risk of dying from their diseas...

Study Confirms CT Screenings Can Cut Lung Cancer Deaths

A new Dutch study is being hailed as proof of the need for annual CT screenings of former and current longtime smokers to reduce deaths from lung cancer.

Dr. Debra Dyer, a spokeswoman for the American College of Radiology and chair of radiology at National Jewish Health in Denver, called the findings "wonderful news."

"There's no doubt about the effectiveness" of annual CT ...

Imaging Technique Tracks Down Stray Lung Cancer Cells for Surgeons

Combining an imaging technology with a new drug that "lights up" lung cancer cells may help surgeons spot hidden bits of cancer, a new study suggests.

The small, preliminary study found that the new combo -- dubbed intraoperative molecular imaging (IMI) -- helped improve outcomes in surgeries of 1 out of 4 patients.

The drug used in IMI is called OTL38. The drug isn't yet ...

Faulty Immune System May Lead to Lung Cancer

An immune system that's not functioning normally may lead to lung cancer in patients who don't smoke, a new study suggests.

"A strong immune system helps to keep inflammation under control and chronic inflammation is known to promote cancer," said co-author Rayjean Hung.

"Our research suggests that it's underlying dysfunction of immune regulation that can lead to lung cance...

Progress Against Lung Cancer Fuels Record Drop in U.S. Cancer Deaths

A 29% drop in U.S. cancer deaths between 1991 and 2017 was driven by declines in deaths from four major cancers -- lung, colon, breast and prostate, according to the latest American Cancer Society (ACS) annual report.

Cancer deaths in the United States fell 2.2% between 2016 and 2017, the largest-ever single-year decrease.

That record drop was spurred by a rapid decl...

Obesity May Boost Effectiveness of a Lung Cancer Therapy

Obesity is seldom a friend to health, but in one medical context it might give patients a slight advantage, new research suggests.

Specifically, when Australian researchers looked at trials of atezolizumab, an immune system-based treatment for lung cancer, they found that the drug worked better in people who were overweight.

The trial involved more than 2,100 people with th...

She Never Smoked -- And Got Lung Cancer in Her 40s

Nikki Moreno had spent nearly a year struggling for breath, and nothing seemed to help.

Not the inhalers, not the antibiotics and other drugs. Nothing seemed to help her breathe, and nothing got rid of her constant cough.

It finally got so bad that she landed in the emergency room at UCLA Medical Center in Santa Monica.

Moreno was not prepared for the series of sho...

Additives to E-Cigarettes May Be Upping Health Dangers

Natural compounds added to marijuana-derived vaping liquid produce toxic chemicals in the vapor that users inhale, a new lab study reports.

The compounds, known as terpenes, are added into pure THC distillations to dilute the product and provide the vapor with aroma and taste, said senior researcher Robert Strongin, a professor of organic chemistry at Portland State University in Ore...

One-Third of Lung Cancer Patients Battle Depression: Study

Depression is common among lung cancer patients and can damage their quality of life and treatment outcomes, a new study indicates.

The findings suggest that doctors should screen lung cancer patients for depression and refer them for mental health care if necessary, said lead author Barbara Andersen, a professor of psychology at Ohio State University in Columbus.

"Depressio...

More Than 1 in 4 High School Students Now Vape: CDC

An epidemic of vaping by American teenagers shows no signs of stopping, with 2019 data finding more than a quarter (27.5%) of high school students using e-cigarettes.

The rate was somewhat lower, but still troubling, among middle school kids -- about 1 in every 10 vaped, according to new research from the U.S. Centers for Disease Control and Prevention.

And just as happ...

Ruth Bader Ginsburg Released From Hospital After Health Scare

Supreme Court Justice Ruth Bader Ginsburg was discharged from the hospital on Sunday after being admitted on Friday with chills and a fever.

The news of her recovery and return home was issued by a court spokeswoman, ABC News reported.

The 86-year-old was first evaluated on Friday at a hospital in Washington, D.C., after feeling unwell. She was then transferred to The...